(1) to soften, dissolve and absorb

When factor Ⅻ is activated, the activation of factor Ⅻ has begun to activate the fibrin dissolve enzyme system, cracking fibrinogen and fibrin, continuous existence and growth of blood clots, or softened, dissolution, absorption, depending on the blood coagulation system and activity comparison between fibrin dissolve enzyme system. When the amount of enzyme that dissolves the thrombus component is large and the activity is strong, the thrombus can be dissolved, and the small thrombus can be completely dissolved and absorbed.

(2) mechanization and re-connection

Machine after thrombosis, and from the vessel wall to thrombus.cause endothelial cells and fibroblasts, and granulation tissue formation, platelet platelet growth factors may play a prompt granulation tissue growth. Granulation tissue protrudes into the thrombus and is gradually replaced by mechanisation. The process of mechanization begins as early as 1 to 2 days after the formation of thrombus, and the larger thrombus can complete mechanization in about 2 weeks. Mechanical thrombus and blood vessel wall have firm adhesion, there is no risk of falling off. Thrombus organization of endothelial cells, new coating crack caused by blood clots dry blood clots, pipeline formed lost but can communicate with each other, a blood clot, upstream and downstream of the blood flow to part of the communication, this phenomenon is called recanalization (recanalization). Intracavitary mononuclear cells can also be from the blood through the free surface of invading the thrombus, which in turn into vascular endothelial cells, form new blood vessels, so the thrombus machine and recanalization is not totally depends on the composition of vessel wall cells invasion.

(3) calcification

Long-term thrombus is neither dissolved nor fully mechanized, calcium and salt deposits can occur. Phlebolith is formed in the vein, and arteriolith can also be used.